For our Miracle Patch Microcrystal Spot Cover, the sweet spot is 4 to 8 hours, or until the patch turns white. That color change is your signal that the microcrystals have dissolved. Press it firmly onto clean, dry skin so the crystals make full contact, then leave it alone, no peeking or repositioning. A lot of people like wearing it overnight so they can just forget about it and check in the morning. Once it's white, peel it off gently and follow with your usual moisturizer. Don't reuse a patch, and stick to one fresh patch per spot per cycle.